In the Middle Ages, Goris was located on the Silk Road connecting Nakhijevan and Syunik with Nagorno-Karabakh (Artsakh) and Central Asia.

From 1870 the modern town developed on the right bank of the Goris River. As of 1885, it was considered as one of the four biggest cities of southern Armenia. At the time, it owned the main market of the Syunik province.